weinreb amide | Weinreb ketone synthesis

Keyword	CPC	PCC	Volume	Score	Length of keyword
weinreb amide	1.16	0.8	153	66	13
weinreb	1.57	0.8	2538	18	7
amide	0.64	0.3	296	24	5

Keyword	CPC	PCC	Volume	Score
weinreb amide	1.56	0.5	7885	69
weinreb amide synthesis	0.31	0.5	7449	45
weinreb amide cas no	0.67	1	8437	73
weinreb amide mechanism	1.96	0.7	2575	82
weinreb amide reaction	0.37	0.3	1180	48
weinreb amide to ketone	0.84	0.9	2445	60
weinreb amide to aldehyde	0.93	0.1	799	12
weinreb amide grignard	0.93	0.4	8247	29
weinreb amide structure	1.34	0.4	6431	73
weinreb amide from carboxylic acid	0.44	0.4	9400	29
weinreb amide reagent	0.11	0.5	250	54
weinreb amide reduction	0.93	0.2	96	15
weinreb amide synthesis from carboxylic acid	0.01	1	7078	24
reduction of weinreb amide to alcohol	0.98	0.8	75	27
weinreb amide formation	1.95	0.9	4907	49
reduction of weinreb amide to aldehyde	0.81	0.9	3777	81

Search Results related to weinreb amide on Search Engine

Weinreb ketone synthesis - Wikipedia
wikipedia.org

https://en.wikipedia.org/wiki/Weinreb_ketone_synthesis

WEBShown below are key steps involving Weinreb amides in the synthesis of several natural products, including members of the immunosuppressant family of macrosphelides, and the antibiotic family of spirofungins. Syntheses using Weinreb–Nahm amide Variations

DA: 35 PA: 100 MOZ Rank: 97

Synthesis of hydroxamates (Weinreb amides) - Organic …
organic-chemistry.org

https://www.organic-chemistry.org/synthesis/C1N/hydroxamates.shtm

WEBA one-pot method allows the synthesis of α-siloxy-Weinreb amides from aldehydes using N,O-dimethylhydroxylamine and a masked acyl cyanide reagent bearing a tert-butyldimethylsilyl group. The TBS group avoids the competitive reaction toward N -methoxy- N -methyl-2-amino-1-siloxymalononitrile.

DA: 14 PA: 88 MOZ Rank: 92

Weinreb Amide - an overview | ScienceDirect Topics
sciencedirect.com

https://www.sciencedirect.com/topics/chemistry/weinreb-amide

WEBThe precursor Weinreb amide 108 was constructed from the commercially available l-tyrosine derivative 106 which was converted to the O-benzyl ether, hydrolyzed to the carboxylic acid 107 and then converted to the amide under standard coupling conditions.

DA: 71 PA: 84 MOZ Rank: 26

A Powerful Reagent for Synthesis of Weinreb Amides Directly …
acs.org

https://pubs.acs.org/doi/10.1021/ol901886u

WEBAbstract. A powerful reagent, P [NCH 3 (OCH 3 )] 3 ( 3 ), for conversion of carboxylic acids directly to Weinreb amides was developed. In most cases the yields of the corresponding Weinreb amides were above 90% when P [NCH 3 (OCH 3 )] 3 was heated with aromatic and aliphatic carboxylic acids in toluene. The sterically hindered carboxylic acids ...

DA: 58 PA: 97 MOZ Rank: 97

(PDF) Recent Developments in Weinreb Synthesis and Their
researchgate.net

https://www.researchgate.net/publication/338271251_Recent_Developments_in_Weinreb_Synthesis_and_Their_Applications_A-Review

WEBDec 31, 2019 · PDF | N-methoxy-N-methyl amides or Weinreb amides are worthy embranchment of amide group and their rich functional groups in organic synthesis become a... | Find, read and cite all the...

DA: 41 PA: 50 MOZ Rank: 26

Chemodivergent transformations of amides using - Nature
nature.com

https://www.nature.com/articles/s41467-020-16948-5

WEBJun 19, 2020 · Weinreb amide (T2) reacted to give low yield of ketone K1. The reactions proceeded smoothly for tertiary amides bearing N -Me- N -Ph ( T3 ) and pyrrolidin-1-yl ( T4 ) groups, affording the...

DA: 31 PA: 97 MOZ Rank: 15

Weinreb Amidation as the Cornerstone of an Improved Synthetic …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268516/

WEBSep 25, 2012 · Weinreb amidation of ethyl 4- oxo -3,4-dihydroquinazoline-2-carboxylate with aromatic amines provides a significantly improved route to anilide-type key intermediates for the synthesis of the anticancer alkaloid, luotonin A, and new A-ring-modified derivatives thereof.

DA: 47 PA: 7 MOZ Rank: 31

Molecules | Free Full-Text | Weinreb Amides as Directing Groups …
mdpi.com

https://www.mdpi.com/1420-3049/24/5/830

WEBJan 28, 2019 · Weinreb amides are a privileged, multi-functional group with well-established utility in classical synthesis. Recently, several studies have demonstrated the use of Weinreb amides as interesting substrates in transition metal-catalyzed C-H functionalization reactions.

DA: 1 PA: 9 MOZ Rank: 90

A redox-neutral synthesis of ketones by coupling of alkenes and amides
nature.com

https://www.nature.com/articles/s41467-019-10151-x

WEBMay 24, 2019 · The advent of the venerable Weinreb amides and related derivatives 3, 4 offered a robust solution to the overaddition issue and triggered the development of related procedures relying on...

DA: 30 PA: 47 MOZ Rank: 32

A Photochemical Protocol for the Synthesis of Weinreb and …
sciencedirect.com

https://www.sciencedirect.com/org/science/article/pii/S1434193X2300525X

WEBIntroduction. Weinreb amides are versatile building blocks that have found wide applications as intermediates for the preparation of aldehydes and ketones from various carboxylic acid derivatives and for the clean and effective acylation of organolithium or organomagnesium reagents. [1]

DA: 47 PA: 21 MOZ Rank: 87