Locoid Lipocream (Hydrocortisone Butyrate): Side Effects, Uses …
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Hypothalamic-Pituitary-Adrenal (HPA) Axis SuppressionConcomitant Skin InfectionsAllergic Contact DermatitisCarcinogenesis, Mutagenesis, Impairment of FertilityPregnancyNursing MothersPediatric Use In a 2-year dermalrat carcinogenicity study with Locoid Lotion, hydrocortisone butyrate was administered to Sprague-Dawley rats at topical doses of 0.05, 0.15, and 0.3 mg/kg/day in males and 0.1, 0.25, and 0.5 mg/kg/day in females (0.1% lotion). No drug-related tumors were noted in this study up to the highest doses evaluated in this study of 0.3 m...
In a 2-year dermalrat carcinogenicity study with Locoid Lotion, hydrocortisone butyrate was administered to Sprague-Dawley rats at topical doses of 0.05, 0.15, and 0.3 mg/kg/day in males and 0.1, 0.25, and 0.5 mg/kg/day in females (0.1% lotion). No drug-related tumors were noted in this study up to the highest doses evaluated in this study of 0.3 m...
DA: 76 PA: 47 MOZ Rank: 65