Keyword Analysis & Research: carafate moa

nih.gov

https://www.ncbi.nlm.nih.gov/books/NBK551527/

WEBFeb 25, 2022 · Sucralfate is a medication used to treat duodenal ulcers, epithelial wounds, chemotherapy-induced mucositis, radiation proctitis, ulcers in Behcet disease, and burn wounds. Sucralfate exhibits its action by forming a protective layer, increasing bicarbonate production, exhibiting anti-peptic effects, promoting tissue growth, regeneration, and ...

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drugbank.com

https://go.drugbank.com/drugs/DB00364

WEBSucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers Label, gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia 2.

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uptodate.com

https://www.uptodate.com/contents/antiulcer-medications-mechanism-of-action-pharmacology-and-side-effects

WEBFeb 21, 2024 · Mechanism of action — Histamine-2 receptor antagonists (H2RAs) (eg, cimetidine, famotidine, and nizatidine) inhibit acid secretion by blocking H2 receptors on the parietal cell ( figure 1 ). H2RAs are well absorbed after oral dosing; peak serum concentrations occur within one to three hours. Absorption is reduced 10 to 20 percent …

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/6798100/

WEBSucralfate also binds to uninjured mucosa and is believed to exert a similar "barrier" effect on regenerated and normal mucosa. Other possible mechanism for sucralfate's antiulcer effect include depletion of acid, pepsin, and bile salts from the the gastric secretion. Animal data show that the action of sucralfate is sustained because of its ...

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wikipedia.org

https://en.wikipedia.org/wiki/Sucralfate

WEBSucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. Its usefulness in people infected by H. pylori is limited.

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nejm.org

https://www.nejm.org/doi/full/10.1056/NEJM199110033251407

WEBSucralfate (Carafate, Marion Merrell Dow, Kansas City, Mo.) is a complex salt of sucrose sulfate and aluminum hydroxide; its structure is shown in Figure 1. It is very poorly soluble in water,... moa

moa

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drugs.com

https://www.drugs.com/carafate.html

WEBMar 27, 2024 · Carafate is an anti-ulcer medication. Carafate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts. Carafate is used to treat an active duodenal ulcer.

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medicine.com

https://www.medicine.com/drug/sucralfate/hcp

WEBFeb 10, 2020 · Last updated February 6, 2020. Includes Sucralfate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

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medscape.com

https://reference.medscape.com/drug/carafate-sucralfate-342006

WEBMedscape - Indication-specific dosing for Carafate (sucralfate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost...

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nih.gov

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c87c6b50-6977-4fa7-ae98-40c0753f7aee

WEBJun 23, 2023 · CARAFATE ® (sucralfate) is indicated in: Short-term treatment (up to 8 weeks) of active duodenal ulcer. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.

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